Years have passed for legendary assassin Ezio Auditore da Firenze since avenging the death of his family for Assassin's Creed 2. Relaxing in his villa in Monteriggioni after a romp between the sheets with a lady friend, Ezio is shaken out of a peaceful cuddle. An attack on the town is in full swing and -- after a cannonball crashes through his bedroom, crushing his armor -- Ezio rushes out to find waves of enemy forces at his doorstep.

Outside his home, Ezio's uncle explains that his status in the region as a legendary assassin has split factions and incites a war between families. To counteract the mass-scale attack, Ezio pushes toward defensive cannon emplacements scattered on the wall of Monteriggioni. It isn't a scene that will end in the assassin's favor; rest assured that Monteriggioni will fall. This is the beginning and the basis for Assassin's Creed: Brotherhood.